High-resolution 3D volumetry versus conventional measuring techniques for the assessment of experimental lymphedema in the mouse hindlimb
Identifieur interne : 001010 ( Main/Exploration ); précédent : 001009; suivant : 001011High-resolution 3D volumetry versus conventional measuring techniques for the assessment of experimental lymphedema in the mouse hindlimb
Auteurs : Florian S. Frueh [Allemagne, Suisse] ; Christina Körbel [Allemagne] ; Laura Gassert [Allemagne] ; Andreas Müller [Allemagne] ; Epameinondas Gousopoulos [Suisse] ; Nicole Lindenblatt [Suisse] ; Pietro Giovanoli [Suisse] ; Matthias W. Laschke [Allemagne] ; Michael D. Menger [Allemagne]Source :
- Scientific Reports [ 2045-2322 ] ; 2016.
Abstract
Secondary lymphedema is a common complication of cancer treatment characterized by chronic limb swelling with interstitial inflammation. The rodent hindlimb is a widely used model for the evaluation of novel lymphedema treatments. However, the assessment of limb volume in small animals is challenging. Recently, high-resolution three-dimensional (3D) imaging modalities have been introduced for rodent limb volumetry. In the present study we evaluated the validity of microcomputed tomography (μCT), magnetic resonance imaging (MRI) and ultrasound in comparison to conventional measuring techniques. For this purpose, acute lymphedema was induced in the mouse hindlimb by a modified popliteal lymphadenectomy. The 4-week course of this type of lymphedema was first assessed in 6 animals. In additional 12 animals, limb volumes were analyzed by μCT, 9.4 T MRI and 30 MHz ultrasound as well as by planimetry, circumferential length and paw thickness measurements. Interobserver correlation was high for all modalities, in particular for μCT analysis (r = 0.975, p < 0.001). Importantly, caliper-measured paw thickness correlated well with μCT (r = 0.861), MRI (r = 0.821) and ultrasound (r = 0.800). Because the assessment of paw thickness represents a time- and cost-effective approach, it may be ideally suited for the quantification of rodent hindlimb lymphedema.
Url:
DOI: 10.1038/srep34673
PubMed: 27698469
PubMed Central: 5048170
Affiliations:
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Frueh</name><affiliation wicri:level="1"><nlm:aff id="a1"><institution>Institute for Clinical and Experimental Surgery, Saarland University</institution>, 66421 Homburg/Saar,<country>Germany</country></nlm:aff><country xml:lang="fr">Allemagne</country><wicri:regionArea># see nlm:aff country strict</wicri:regionArea></affiliation><affiliation wicri:level="1"><nlm:aff id="a2"><institution>Division of Plastic Surgery and Hand Surgery, University Hospital Zurich</institution>, 8091 Zurich,<country>Switzerland</country></nlm:aff><country xml:lang="fr">Suisse</country><wicri:regionArea># see nlm:aff country strict</wicri:regionArea></affiliation></author><author><name sortKey="Korbel, Christina" sort="Korbel, Christina" uniqKey="Korbel C" first="Christina" last="Körbel">Christina Körbel</name><affiliation wicri:level="1"><nlm:aff id="a1"><institution>Institute for Clinical and Experimental Surgery, Saarland University</institution>, 66421 Homburg/Saar,<country>Germany</country></nlm:aff><country xml:lang="fr">Allemagne</country><wicri:regionArea># see nlm:aff country strict</wicri:regionArea></affiliation></author><author><name sortKey="Gassert, Laura" sort="Gassert, Laura" uniqKey="Gassert L" first="Laura" last="Gassert">Laura Gassert</name><affiliation wicri:level="1"><nlm:aff id="a1"><institution>Institute for Clinical and Experimental Surgery, Saarland University</institution>, 66421 Homburg/Saar,<country>Germany</country></nlm:aff><country xml:lang="fr">Allemagne</country><wicri:regionArea># see nlm:aff country strict</wicri:regionArea></affiliation></author><author><name sortKey="Muller, Andreas" sort="Muller, Andreas" uniqKey="Muller A" first="Andreas" last="Müller">Andreas Müller</name><affiliation wicri:level="1"><nlm:aff id="a3"><institution>Clinic of Diagnostic and Interventional Radiology, Saarland University Medical Center</institution>, Homburg/Saar,<country>Germany</country></nlm:aff><country xml:lang="fr">Allemagne</country><wicri:regionArea># see nlm:aff country strict</wicri:regionArea></affiliation></author><author><name sortKey="Gousopoulos, Epameinondas" sort="Gousopoulos, Epameinondas" uniqKey="Gousopoulos E" first="Epameinondas" last="Gousopoulos">Epameinondas Gousopoulos</name><affiliation wicri:level="1"><nlm:aff id="a4"><institution>Institute of Pharmaceutical Sciences, Swiss Federal Institute of Technology</institution>, ETH Zurich, Zurich,<country>Switzerland</country></nlm:aff><country xml:lang="fr">Suisse</country><wicri:regionArea># see nlm:aff country strict</wicri:regionArea></affiliation></author><author><name sortKey="Lindenblatt, Nicole" sort="Lindenblatt, Nicole" uniqKey="Lindenblatt N" first="Nicole" last="Lindenblatt">Nicole Lindenblatt</name><affiliation wicri:level="1"><nlm:aff id="a2"><institution>Division of Plastic Surgery and Hand Surgery, University Hospital Zurich</institution>, 8091 Zurich,<country>Switzerland</country></nlm:aff><country xml:lang="fr">Suisse</country><wicri:regionArea># see nlm:aff country strict</wicri:regionArea></affiliation></author><author><name sortKey="Giovanoli, Pietro" sort="Giovanoli, Pietro" uniqKey="Giovanoli P" first="Pietro" last="Giovanoli">Pietro Giovanoli</name><affiliation wicri:level="1"><nlm:aff id="a2"><institution>Division of Plastic Surgery and Hand Surgery, University Hospital Zurich</institution>, 8091 Zurich,<country>Switzerland</country></nlm:aff><country xml:lang="fr">Suisse</country><wicri:regionArea># see nlm:aff country strict</wicri:regionArea></affiliation></author><author><name sortKey="Laschke, Matthias W" sort="Laschke, Matthias W" uniqKey="Laschke M" first="Matthias W." last="Laschke">Matthias W. Laschke</name><affiliation wicri:level="1"><nlm:aff id="a1"><institution>Institute for Clinical and Experimental Surgery, Saarland University</institution>, 66421 Homburg/Saar,<country>Germany</country></nlm:aff><country xml:lang="fr">Allemagne</country><wicri:regionArea># see nlm:aff country strict</wicri:regionArea></affiliation></author><author><name sortKey="Menger, Michael D" sort="Menger, Michael D" uniqKey="Menger M" first="Michael D." last="Menger">Michael D. Menger</name><affiliation wicri:level="1"><nlm:aff id="a1"><institution>Institute for Clinical and Experimental Surgery, Saarland University</institution>, 66421 Homburg/Saar,<country>Germany</country></nlm:aff><country xml:lang="fr">Allemagne</country><wicri:regionArea># see nlm:aff country strict</wicri:regionArea></affiliation></author></analytic><series><title level="j">Scientific Reports</title><idno type="eISSN">2045-2322</idno><imprint><date when="2016">2016</date></imprint></series></biblStruct></sourceDesc></fileDesc><profileDesc><textClass></textClass></profileDesc></teiHeader><front><div type="abstract" xml:lang="en"><p>Secondary lymphedema is a common complication of cancer treatment characterized by chronic limb swelling with interstitial inflammation. The rodent hindlimb is a widely used model for the evaluation of novel lymphedema treatments. However, the assessment of limb volume in small animals is challenging. Recently, high-resolution three-dimensional (3D) imaging modalities have been introduced for rodent limb volumetry. In the present study we evaluated the validity of microcomputed tomography (μCT), magnetic resonance imaging (MRI) and ultrasound in comparison to conventional measuring techniques. For this purpose, acute lymphedema was induced in the mouse hindlimb by a modified popliteal lymphadenectomy. The 4-week course of this type of lymphedema was first assessed in 6 animals. In additional 12 animals, limb volumes were analyzed by μCT, 9.4 T MRI and 30 MHz ultrasound as well as by planimetry, circumferential length and paw thickness measurements. Interobserver correlation was high for all modalities, in particular for μCT analysis (r = 0.975, p < 0.001). Importantly, caliper-measured paw thickness correlated well with μCT (r = 0.861), MRI (r = 0.821) and ultrasound (r = 0.800). Because the assessment of paw thickness represents a time- and cost-effective approach, it may be ideally suited for the quantification of rodent hindlimb lymphedema.</p></div></front><back><div1 type="bibliography"><listBibl><biblStruct><analytic><author><name sortKey="Cueni, L N" uniqKey="Cueni L">L. N. Cueni</name></author><author><name sortKey="Detmar, M" uniqKey="Detmar M">M. Detmar</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Rockson, S G" uniqKey="Rockson S">S. G. Rockson</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Szuba, A" uniqKey="Szuba A">A. Szuba</name></author><author><name sortKey="Rockson, S G" uniqKey="Rockson S">S. G. Rockson</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Alitalo, K" uniqKey="Alitalo K">K. Alitalo</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Mortimer, P S" uniqKey="Mortimer P">P. S. Mortimer</name></author><author><name sortKey="Rockson, S G" uniqKey="Rockson S">S. G. Rockson</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Karkkainen, M J" uniqKey="Karkkainen M">M. J. Karkkainen</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Bramos, A" uniqKey="Bramos A">A. Bramos</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Avraham, T" uniqKey="Avraham T">T. Avraham</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Hadamitzky, C" uniqKey="Hadamitzky C">C. Hadamitzky</name></author><author><name sortKey="Pabst, R" uniqKey="Pabst R">R. Pabst</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Disipio, T" uniqKey="Disipio T">T. DiSipio</name></author><author><name sortKey="Rye, S" uniqKey="Rye S">S. Rye</name></author><author><name sortKey="Newman, B" uniqKey="Newman B">B. Newman</name></author><author><name sortKey="Hayes, S" uniqKey="Hayes S">S. Hayes</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Frueh, F S" uniqKey="Frueh F">F. S. Frueh</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Mendez, U" uniqKey="Mendez U">U. Mendez</name></author><author><name sortKey="Brown, E M" uniqKey="Brown E">E. M. Brown</name></author><author><name sortKey="Ongstad, E L" uniqKey="Ongstad E">E. L. Ongstad</name></author><author><name sortKey="Slis, J R" uniqKey="Slis J">J. R. Slis</name></author><author><name sortKey="Goldman, J" uniqKey="Goldman J">J. Goldman</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Mendez, U" uniqKey="Mendez U">U. Mendez</name></author><author><name sortKey="Stroup, E M" uniqKey="Stroup E">E. M. Stroup</name></author><author><name sortKey="Lynch, L L" uniqKey="Lynch L">L. L. Lynch</name></author><author><name sortKey="Waller, A B" uniqKey="Waller A">A. B. Waller</name></author><author><name sortKey="Goldman, J" uniqKey="Goldman J">J. Goldman</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Tammela, T" uniqKey="Tammela T">T. Tammela</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Aschen, S Z" uniqKey="Aschen S">S. Z. Aschen</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Cheng, M H" uniqKey="Cheng M">M. H. Cheng</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Joseph, W J" uniqKey="Joseph W">W. J. Joseph</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Nguyen, D H" uniqKey="Nguyen D">D. H. Nguyen</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Hwang, J H" uniqKey="Hwang J">J. H. Hwang</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Yoshida, S" uniqKey="Yoshida S">S. Yoshida</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Sommer, T" uniqKey="Sommer T">T. Sommer</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Yang, C Y" uniqKey="Yang C">C. Y. Yang</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Schneider, C A" uniqKey="Schneider C">C. A. Schneider</name></author><author><name sortKey="Rasband, W S" uniqKey="Rasband W">W. S. Rasband</name></author><author><name sortKey="Eliceiri, K W" uniqKey="Eliceiri K">K. W. Eliceiri</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Baumeister, R G" uniqKey="Baumeister R">R. G. Baumeister</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Koshima, I" uniqKey="Koshima I">I. Koshima</name></author><author><name sortKey="Inagawa, K" uniqKey="Inagawa K">K. Inagawa</name></author><author><name sortKey="Urushibara, K" uniqKey="Urushibara K">K. Urushibara</name></author><author><name sortKey="Moriguchi, T" uniqKey="Moriguchi T">T. Moriguchi</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Becker, C" uniqKey="Becker C">C. Becker</name></author><author><name sortKey="Assouad, J" uniqKey="Assouad J">J. Assouad</name></author><author><name sortKey="Riquet, M" uniqKey="Riquet M">M. Riquet</name></author><author><name sortKey="Hidden, G" uniqKey="Hidden G">G. Hidden</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="L Hteenvuo, M" uniqKey="L Hteenvuo M">M. Lähteenvuo</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Honkonen, K M" uniqKey="Honkonen K">K. M. Honkonen</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Hwang, J H" uniqKey="Hwang J">J. H. Hwang</name></author><author><name sortKey="Lee, C H" uniqKey="Lee C">C. H. Lee</name></author><author><name sortKey="Lee, H H" uniqKey="Lee H">H. H. Lee</name></author><author><name sortKey="Kim, S Y" uniqKey="Kim S">S. Y. Kim</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Sevick Muraca, E M" uniqKey="Sevick Muraca E">E. M. Sevick-Muraca</name></author><author><name sortKey="Kwon, S" uniqKey="Kwon S">S. Kwon</name></author><author><name sortKey="Rasmussen, J C" uniqKey="Rasmussen J">J. C. Rasmussen</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Kobayashi, H" uniqKey="Kobayashi H">H. Kobayashi</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Pan, D" uniqKey="Pan D">D. Pan</name></author><author><name sortKey="Suzuki, Y" uniqKey="Suzuki Y">Y. Suzuki</name></author><author><name sortKey="Yang, P C" uniqKey="Yang P">P. C. Yang</name></author><author><name sortKey="Rockson, S G" uniqKey="Rockson S">S. G. Rockson</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Mounzer, R" uniqKey="Mounzer R">R. Mounzer</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Hayashi, K" uniqKey="Hayashi K">K. Hayashi</name></author><author><name sortKey="Nakamura, M" uniqKey="Nakamura M">M. Nakamura</name></author><author><name sortKey="Ishimura, K" uniqKey="Ishimura K">K. Ishimura</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Martel, C" uniqKey="Martel C">C. Martel</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Shejawal, N" uniqKey="Shejawal N">N. Shejawal</name></author><author><name sortKey="Menon, S" uniqKey="Menon S">S. Menon</name></author><author><name sortKey="Shailajan, S" uniqKey="Shailajan S">S. Shailajan</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Lee Donaldson, L" uniqKey="Lee Donaldson L">L. Lee-Donaldson</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Oashi, K" uniqKey="Oashi K">K. Oashi</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Park, H S" uniqKey="Park H">H. S. Park</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Damstra, R J" uniqKey="Damstra R">R. J. Damstra</name></author><author><name sortKey="Glazenburg, E J" uniqKey="Glazenburg E">E. J. Glazenburg</name></author><author><name sortKey="Hop, W C" uniqKey="Hop W">W. C. Hop</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Pan, D" uniqKey="Pan D">D. Pan</name></author><author><name sortKey="Han, J" uniqKey="Han J">J. Han</name></author><author><name sortKey="Wilburn, P" uniqKey="Wilburn P">P. Wilburn</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Shioya, R" uniqKey="Shioya R">R. Shioya</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Fajardo, K A" uniqKey="Fajardo K">K. A. Fajardo</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Zhou, H F" uniqKey="Zhou H">H. F. Zhou</name></author><author><name sortKey="Chan, H W" uniqKey="Chan H">H. W. Chan</name></author><author><name sortKey="Wickline, S A" uniqKey="Wickline S">S. A. Wickline</name></author><author><name sortKey="Lanza, G M" uniqKey="Lanza G">G. M. Lanza</name></author><author><name sortKey="Pham, C T" uniqKey="Pham C">C. T. Pham</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Xin, W" uniqKey="Xin W">W. Xin</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Laperre, K" uniqKey="Laperre K">K. Laperre</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Fenster, A" uniqKey="Fenster A">A. Fenster</name></author><author><name sortKey="Downey, D B" uniqKey="Downey D">D. B. Downey</name></author><author><name sortKey="Cardinal, H N" uniqKey="Cardinal H">H. N. Cardinal</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Bland, J M" uniqKey="Bland J">J. M. Bland</name></author><author><name sortKey="Altman, D G" uniqKey="Altman D">D. G. Altman</name></author></analytic></biblStruct></listBibl></div1></back></TEI><affiliations><list><country><li>Allemagne</li><li>Suisse</li></country></list><tree><country name="Allemagne"><noRegion><name sortKey="Frueh, Florian S" sort="Frueh, Florian S" uniqKey="Frueh F" first="Florian S." last="Frueh">Florian S. Frueh</name></noRegion><name sortKey="Gassert, Laura" sort="Gassert, Laura" uniqKey="Gassert L" first="Laura" last="Gassert">Laura Gassert</name><name sortKey="Korbel, Christina" sort="Korbel, Christina" uniqKey="Korbel C" first="Christina" last="Körbel">Christina Körbel</name><name sortKey="Laschke, Matthias W" sort="Laschke, Matthias W" uniqKey="Laschke M" first="Matthias W." last="Laschke">Matthias W. Laschke</name><name sortKey="Menger, Michael D" sort="Menger, Michael D" uniqKey="Menger M" first="Michael D." last="Menger">Michael D. Menger</name><name sortKey="Muller, Andreas" sort="Muller, Andreas" uniqKey="Muller A" first="Andreas" last="Müller">Andreas Müller</name></country><country name="Suisse"><noRegion><name sortKey="Frueh, Florian S" sort="Frueh, Florian S" uniqKey="Frueh F" first="Florian S." last="Frueh">Florian S. Frueh</name></noRegion><name sortKey="Giovanoli, Pietro" sort="Giovanoli, Pietro" uniqKey="Giovanoli P" first="Pietro" last="Giovanoli">Pietro Giovanoli</name><name sortKey="Gousopoulos, Epameinondas" sort="Gousopoulos, Epameinondas" uniqKey="Gousopoulos E" first="Epameinondas" last="Gousopoulos">Epameinondas Gousopoulos</name><name sortKey="Lindenblatt, Nicole" sort="Lindenblatt, Nicole" uniqKey="Lindenblatt N" first="Nicole" last="Lindenblatt">Nicole Lindenblatt</name></country></tree></affiliations></record>Pour manipuler ce document sous Unix (Dilib)
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